Case Study – CLEANING VERIFICATION

Cleaning Verification and Validation Site Gap Evaluation Cancer Therapies United States – Confidential Client Download this case study Project Description Hyde performed a thorough gap analysis of the Cleaning Program for a drug product in short supply that was being manufactured at a contract manufacturing facility under consent decree. Hyde’s work on the project involved […]

Case Study – TRITON X WASTEWATER RESTRICTIONS

Rinsability Study Triton X Wastewater Restrictions Confidential Client Download this case study Study Overview The laboratory conducted a small-scale rinsing method using a specific Ultrahigh Performance Liquid Chromatography (UHPLC) method to determine the necessary volume of water per surface area to remove Triton X from full-scale tanks. This rinse volume is collected for proper disposal […]

Case Study – LEGACY CLEANING

Hyde Analytical Lab Legacy Cleaning Process Optimization Ireland – MSD Swords Manufacturing Facility United States Download this case study Mechanical Services GREATER CLEANING EFFICIENCY Cleaning Process Design of Experiments (DOE) Study COMPLETE SPRAY COVERAGE New pipe work & spray ball locations in Bolz vessel based on computer imaging INCREASED THERMAL MASS New 6kW Air Heater […]

Case Study – DRUG SUBSTANCE FACILITY DESIGN

Engineering Drug Substance Manufacturing Facility Design EPCMV Cell Culture EPCMV Cell Culture China – Confidential Client Download this case study Project Description This was a Greenfield multi-product drug substance facility. The facility was designed with hybrid equipment, developing an optimum mix between single use technology and stainless steel equipment. The equipment systems included media prep, […]